The OpenArray Real-Time qPCR platform delivers quantitative methylation-specific PCR (qMSP). Find correlations between methylation status and clinicopathological status. With one flexible tool you can identify genes inactivated bt hypermethylation and quickly switch to a screening protocol to group 100's of samples a day based on gene methylation profile.
Traditional methods for methylation-specific PCR are laborious and often do not provide quntitative measures of methylation. The OpenArray platform provides a better means of performing high-throughput methylation studies as each OpenArray plate can perform almost 3000 real-time PCR reactions.
Resources
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Biomarker Discovery using qMSP (Application note)
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James M. Dixon, Mariusz Lubomirski, Dhammika Amaratunga, Tom B. Morrison, Colin J. H. Brenan and Sergey E. Ilyin. BioTechniques 46:ii-viii. |
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OpenArray DLP Product ProfileA summary of how customers use the OpenArray platform with TaqMan® chemistry. In addition, there is information about our workflow and analysis software. |