With OpenArray DLP researchers are able to profile the complete set of human microRNAs against 36 separate samples in just one day. MicroRNA profiling has never been easier! The highly flexible format of the OpenArray plate allows researchers to very easily switch from discovery phase to screening phase of miRNA studies. Currently, researchers profile miRNAs either by using less than trustworthy hybridization techniques or hand-cramping 384-well plate-based qPCR systems. Using the OpenArray technology provides the benefits from the parallelism of microarrays and the data quality of Real-Time qPCR.
Whether you are interested in discovering miRNA-based expression markers, understanding the complex nature of post-transcriptional gene regulation or identifying the numerous targets of miRNAs and off-target effects of siRNAs, the OpenArray platform is the way to go. Currently, OpenArray is being used by some of the leaders in the miRNA field to discover differentially expressed miRNAs as well as their target mRNAs.
Resources
(Please click on image or link to download)
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OpenArray DLP Product ProfileA summary of how customers use the OpenArray platform with TaqMan chemistry. In addition, there is information about our workflow and analysis software. |
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Expression Profiling of both miRNAs and mRNA targetsAndrew T. Bond, Elena Grigorenko, Elen Ortenberg, James Hurley, James White and Kevin Munnell. ESHG 2009. |
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Nanoliter high-throughput RT-qPCR: a statistical ....James M. Dixon, Mariusz Lubomirski, Dhammika Amaratunga, Tom B. Morrison, Colin J. H. Brenan and Sergey E. Ilyin. BioTechniques 46:ii-viii. |