Gene Expression Profiling using OpenArray

Validation of DNA array results is one of the most common uses of qPCR.  Generally, with tedious plate-based systems researchers need to narrow their focus to keep projects to a manageable size.  Using OpenArray to validate microarray hits allows you to cast a wide net; choosing genes that may be expressed at a lower level or that have a differential expression ratio less than 2-fold.

It has been shown that the OpenArray platform identifies differentially expressed genes below the sensitivity threshold of common chip and bead-based microarray platforms.  The OpenArray Pathways panels allow you to use the OpenArray platform in a discovery mode; uncovering differentially expressed genes.  Let's put the hypothesis back into research.

Resources
(Please click on image or link to download)

	Pathways Product Profile A complete and current listing of the Pathways panels available.  Each Pathways panel contains 600+ bench-validated assays for genes involved in common disease processes or biological pathways.
	Nanoliter high-throughput RT-qPCR: a statistical .... James M. Dixon, Mariusz Lubomirski, Dhammika Amaratunga, Tom B. Morrison, Colin J. H. Brenan and Sergey E. Ilyin.  BioTechniques 46:ii-viii.
	OpenArray DLP Product Profile A summary of how customers use the OpenArray platform with TaqMan® chemistry.  In addition, there is information about our workflow and analysis software.
	Identification of Differentially Expressed Gene..... Andrew T. Bond, D. Roberts, E. Grigorenko, E. Ortenberg, K. Munnelly.  PAG 2009.