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RapidFire HTMS System

RapidFire HTMS System Header

The RapidFire high-throughput mass spectrometry (RF-MS) hardware system is a native detection technology for cytochrome P450 inhibition assays and screening of chemical libraries against biochemical assays. RF-MS facilitates the label-free detection of multiple analytes in a wide range of applications, greatly streamlining assay development for novel assays and providing biologically relevant data.

RapidFire Generation II High-Throughput Mass Spectrometry System

The newly developed system incorporates many upgrades and improvements and has been designed to allow walk-away automation to provide greater throughput and flexibility for primary screening applications. It additionally incorporates many user-selectable options to improve the data quality of the system for secondary screening and follow up along with P450 inhibition assays.

Features:

  • Integrated online sample preparation and analysis system with throughputs up to 6 seconds per sample
  • No sample preparation prior to analysis required - simply quench your assay plates and load them into the RapidFire HT-MS system for analysis.
  • Fully compatible with SBS standard 96 and 384-well plates including deep-well and low-volume plates
  • Walk-away, fully automated operation automation for up to 18 microtiter plates or up to 6 hours of operation
  • New data analysis and report generation software to export high-throughput screening and ADME data into databases and spreadsheets
  • Fully automated, user-selectable multi-solvent flushing of autosampler and the ability to introduce blank injections between samples to minimize sample-to-sample carryover
  • Fast and easy conversion between high-throughput RF-MS and conventional HPLC applications on a single mass spectrometer

For additional information, please email: RapidFire_Info@biotrove.com.

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RapidFire™ CYP450 Screening
High throughput mass spectrometry for DDI assays



RapidFire™ Mass Spectrometry Chromatography System
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