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RapidFire™ Technology
The RapidFire™ Platform: Integrating Mass Spectrometry into the High-Throughput Environment (50 minute presentation)
Analytica Chimica Acta (article in press)
Development of a High Throughput Screening Assay for Stearoyl-CoA Desaturase Using Rat Liver Microsomes, Deuterium Labeled Stearoyl-CoA and Mass Spectrometry
Comb Chem High Throughput Screen. 2008 Mar;11(3):231-7.
Back to basics: label-free technologies for small molecule screening
Agilent Application Note
Ultra-high throughput determination of CYP450 enzyme inhibition through mass spectrometry
Astra-Zeneca Presentation at 2007 AAPS meeting
Comparison of BioTrove RapidFire uHTMS and Traditional LCMS/MS Analysis to Assess Cytochrome P450 Inhibition Utilizing Clinically Relevant Probe Substrates
J Biomol Screen 2007 Jun;12(4):473-80.
High-Throughput Screening by Mass Spectrometry: Comparison with the Scintillation Proximity Assay with a Focused-File Screen of AKT1/PKBα
J Biomol Screen 2007 Aug;12(5):628-634.
High-Throughput Mass Spectrometry Screening for Inhibitors of Phosphatidylserine Decarboxylase
Merck Presentation at 2007 SBS meeting
Identification of Inhibitors for the Phosphatidylethanolamine N-methytransferase Enzyme by High-Throughput Mass Spectrometry Detection of Reaction Products
Bayer Presentation at 2007 SBS meeting
High-Throughput Mass Spectrometry Screening for Inhibitors of Phosphatidylserine Decarboxylase
Amgen Presentation at 2006 ScreenTech meeting
Label-Free Screening Technologies: Validation and Hit-to-Lead Characterization
Schering Plough Research Institute Poster from 2006 SBS meeting
Screening LpxC (UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase) using BioTrove RapidFire HTS Mass Spectrometry
Pfizer Poster from 2006 SBS meeting
Identification of Fatty Acid Amide Hydrolase Inhibitors by a High Throughput Mass Spectrometry-Based Assay
Bayer Poster from 2006 SBS meeting
Label-Free High-Throughput Screening by Mass Spectrometry
Sirtris Pharmaceuticals Poster from 2006 SBS meeting
Development of a High Throughput SIRT1 Mass Spectrometry Assay
BlueSky BioTech Poster from SBS 2006 meeting
Label-Free Screening of Acetyl-CoA Carboxylase from an Enriched Rat Liver Fraction
BlueSky BioTech Poster from SBS 2006 meeting
Label-Free Screening of Stearoyl-Coenzyme A Desaturase from an Enriched Rat Liver Fraction
Pfizer Research Technology Center Poster from 2006 ISSX meeting
High-Throughput Mass Spectrometry-Based Screening to Identify Selective CYP3A5 Inhibitors
Assay Drug Development Technology, August 2004
High Throughput Screening via Mass Spectrometry: A Case Study Using Acetylcholinesterase
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