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BioTrove, Inc. Announces Collaborative Agreement with Pfizer, Inc.

Cambridge, MA, January 12, 2001—BioTrove, Inc., formerly Advanced Instrumentation Systems, Inc., announced today it has entered into a collaborative research agreement with Pfizer Inc. (NYSE:PFE) for the development of BioTrove's ultra-high throughput screening technology for use in Pfizer's research facilities.

Under the terms of the two-year agreement, BioTrove will develop a ultra-high throughput screening platform integrating proprietary nanoscale liquid handling technologies to be purchased by Pfizer for use by Pfizer research sites.

"BioTrove is extremely pleased to have entered into this relationship with Pfizer," said Colin Brenan, Ph.D., Chief Executive Officer and co-founder of BioTrove, Inc. "Pfizer is an innovative research-based company that has recognized the value of technological innovation in accelerating the drug discovery process. BioTrove has created advanced technology purposely designed to speed the analysis of drug compounds in nanoliter volume assays and at high rates. We believe that BioTrove's system will be of great benefit to Pfizer and other companies to accelerate drug development and design."

About BioTrove

BioTrove is a privately-held company providing innovative technological solutions to the life science industry. Their proprietary drug discovery technology platforms are designed to substantially increase the efficiency of the entire pre-clinical drug discovery process from combinatorial chemistry, target identification, through high-performance screening and profiling, to ADME/Tox studies.

For more information contact:

Colin Brenan, C.E.O.
Robert Hess, V.P. Business Development

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